When I had final high-resolution artwork I set about shrinking them and moving panels around for my final book. The web formated pages are around 10″ x 7″, but my book format is around 6″ x 7″. More of a square. I usually planned my drawings in tiers. Each page has two tiers. So to fit the rectangular piece into the more square book I just take one page and add to it half of the next page, creating a three tier final artwork. (What was two rows on the web, is now three in print. I hope that makes sense).
I actually found this all rather helpful.